Research has linked long-term use of the Depo-Provera birth control shot to a significantly higher risk of meningioma, a tumor that grows on the membranes around the brain. Thousands of women are suing Pfizer for failing to warn them. If you used Depo-Provera for a year or more and were later diagnosed with a brain meningioma, you may be entitled to compensation.
Case count per MDL docket reports, fall 2026. Risk figure: Roland et al., BMJ, 2024 (use of 1 year or more).
Depo-Provera is an injectable birth control shot given every three months. Lawsuits claim Pfizer knew or should have known about the link to meningioma brain tumors, but U.S. patients and doctors were not warned.
A large study published in the BMJ found that using the shot for a year or more was linked to about a 5.6 times higher risk of meningioma requiring surgery.
Plaintiffs allege regulators outside the U.S. acted on the risk while American labels stayed silent for years.
In December 2025 the FDA approved a U.S. label update adding a meningioma warning, after many women had already been diagnosed.
Women who used Depo-Provera for years say they were never told the shot could raise their risk of a brain tumor.Allegations from complaints in the Depo-Provera products liability litigation. Pfizer denies these claims.
Meningiomas often grow slowly and can press on the brain and nearby nerves. Symptoms are often mistaken for migraines or other conditions.
Settlement terms have not been made public and are subject to court approval. Eligibility is determined case by case. Submitting a form does not create an attorney-client relationship.
Answer a few quick questions online or call us. It takes about two minutes and is completely confidential.
Our legal team helps gather proof of your Depo-Provera use and diagnosis. You don't need your records in hand to start.
If you have a case, we work on a contingency fee. You pay nothing upfront, and we're only paid if you recover.
Compensation in these cases may help cover:
Women who used the Depo-Provera birth control shot and were later diagnosed with meningioma are suing Pfizer and related companies, claiming they failed to warn patients and doctors about the brain tumor risk. Federal cases are consolidated in MDL No. 3140 in the Northern District of Florida, with related cases in several state courts.
In June 2026 the federal court announced that the parties had reached an initial global settlement agreement. The details have not been made public and must be finalized and approved. A free case review can help you understand whether you may be able to participate and what deadlines apply.
A meningioma is a tumor that forms in the membranes (meninges) surrounding the brain. Most are not cancerous, but they can grow and press on the brain or nerves, causing headaches, vision and hearing problems, seizures, and other symptoms. Many require surgery or radiation.
Yes, you may. Many women were diagnosed years after their last shot. What matters is that you used Depo-Provera for at least a year and were diagnosed with a brain meningioma afterward. Deadlines vary by state, so it's best to get a review soon.
Depo-Provera became available as a generic in 2005. You may qualify if you had at least one year of brand-name Depo-Provera, even if you switched to a generic later. Greenstone and Prasco medroxyprogesterone also qualify. If you're not sure which version you received, we can help find out from your medical or pharmacy records.
No. Each woman files her own individual lawsuit. Cases are grouped together for pretrial proceedings, but each claim is evaluated on its own facts.
Nothing upfront. These cases are handled on a contingency fee basis, which means attorney fees are paid only out of a recovery. If there is no recovery, you owe no attorney fees.
Free, confidential review. No obligation and no upfront cost.
